Stabilization of Microtubules by Taxane Diterpenoids: Insight from Docking and MD simulations
نویسندگان
چکیده
منابع مشابه
Taxane Diterpenoids from Taxus baccata L. Growing in Iran
Background: There are eight Taxus species and two hybrids in the world and Taxus baccata L. (European yew) is the single representative in Iran. Until now, a large number of taxoids possessing different skeleton systems, as well as lignans, flavonoids, steroids and sugar derivatives have been isolated from various Taxus species. Taxoids are highly oxygenated diterpenes isolated from different...
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Five new taxane diterpenoids, taxumairols G (1), H (2), I (3), J (4), and L (5) were isolated from extracts of the roots of Taiwanese Taxus mairei (LEMEE & LEVL.) S. Y. Hu. Compounds 1-4 belong to the new 11(15-->1)-abeo-taxene system, having a tetrahydrofuran ring along carbons C-2, C-3, C-4 and C-20. Compounds 3 and 4 contain an isopropenyl group at C-1 while compounds 1 and 2 are attached wi...
متن کاملtaxane diterpenoids from taxus baccata l. growing in iran
background: there are eight taxus species and two hybrids in the world and taxus baccata l. (european yew) is the single representative in iran. until now, a large number of taxoids possessing different skeleton systems, as well as lignans, flavonoids, steroids and sugar derivatives have been isolated from various taxus species. taxoids are highly oxygenated diterpenes isolated from different s...
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Extensive urbanization has greatly raised the demand for cleaner coal- and petroleum-derived fuels. Mainly composed of methane, natural gas represents a promising alternative for this purpose, making its storage a significant topic. In the present research, deposition of methane molecules in C60 fullerene was investigated through a combined approach wherein density functional based tight bindin...
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ژورنال
عنوان ژورنال: Journal of Biological Physics
سال: 2014
ISSN: 0092-0606,1573-0689
DOI: 10.1007/s10867-014-9369-5